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Initially considered an adaptive immune system disorder, SLE is characterized by high disease activity and the presence of autoreactive antibodies

The key difference lies in receptor targeting: Semaglutide GLP-1 receptor only Tirzepatide GLP-1 + GIP receptors Retatrutide GLP-1 + GIP + glucagon receptors The addition of glucagon receptor activity introduces a potential energy-expenditure component compared with GLP-1-only compounds

Diabetes Ther 10 , 12051217 (2019)

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Management of hyperglycaemia in type 2 diabetes: a patient-centered approach