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We've seen anecdotal reports from the research community where administering PT-141 after a heavy meal pushed the onset time to 5 hours or more, or in some cases, blunted the effects entirely

Provider vigilance and patient education are key for management Image content: This image is available to view online

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Analysis of data from 69 randomised placebo or active comparator-controlled trials of GLP-1 agonists found that no events of NAION were reported in 64 trials

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Phase 3 trials are currently underway to confirm these results in larger populations and evaluate long-term safety