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Clinical trials show average weight loss of 15-22% over 68 weeks on semaglutide alone, with some patients reaching 25%+ loss

QS: Data curation, Methodology, Project administration, Writing original draft

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Weight Loss Medication Tracker Phaze supports 14 GLP-1 medication options including Ozempic, Mounjaro, Wegovy, Wegovy Pill, Zepbound, Rybelsus, Retatrutide, Survodutide, Orforglipron, Pemvidutide, Bioglutida, and CagriSema

Despite these benefits, these trials assessed cardiovascular clinical endpoints rather than myocardial structure or ECM collagen deposition, and thus do not establish a fibrosis-mediated mechanism

doi: 10.1093/toxsci/57.2.338