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In an overweight-adult randomized controlled trial, this raised postprandial GLP-1 and PYY and reduced food intake acutely

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According to the MHRA-approved SmPC, treatment should be discontinued after 12 weeks on the 3.0 mg/day dose if patients have not lost at least 5% of their initial body weight

When adjusting the hematocrit to 4%, the increase in PS-exposing cells was still observed, albeit to a lesser extent (from 5% to 10% of PS-exposing cells, p =0.0083)

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These results suggest that PLC-3 can be used as a therapeutic target to inhibit tumor angiogenesis