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We are not aware of any basis for compounding a drug using these semaglutide salts that would meet federal law requirements that limit the type of active ingredients that can be used in compounding. The FDAs subsequent, May 31, 2023, bulletin also mirrors the language used in its NABP letter

The medication is administered as a once-weekly subcutaneous injection and functions through several mechanisms

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According to a 2017 study by Martinak et al., published in Psychopharmacology Bulletin , dextromethorphan abuse results in significant psychiatric symptoms, highlighting its potential for misuse