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In another study from 2023 in which people were given tirzepatidea newer drug that targets GLP-1 and a similar metabolic hormone called glucose-dependent insulinotropic polypeptide (GIP)participants kept off almost 10 percent of their weight a year after they stopped taking the medication

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The treatment period was then split into two insulin dosing stages: a capped insulin period during which total daily insulin dosage was not to exceed the dosage at randomization (weeks 826), followed by a period during which total daily insulin dosage was freely adjustable at the discretion of the investigator (weeks 2652)

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