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Interestingly, BSO induced depletion of GSH had no effect on rotenone induced ROS nor cell death, which indicates that it was not possible to decrease the GSH level further and thus no increase in cytotoxicity compare to rotenone alone in the RTgill-W1 cells

Weight loss therapy should only be considered if the patient is genuinely overweight or obese and nutritionally replete

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This shift in perception is vital for reducing the stigma that has prevented many patients from seeking help in the past

Gradual adaptations tend to be more easily embraced and sustained over time

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