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NAC benefits include: Direct glutathione precursor support Improved antioxidant status Better detoxification capacity Better respiratory health Most studies use doses between 600-1800mg daily

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After 6 h of treatment the GSH:GSSG ratio had decreased by 85% to 2.6:1 (Figure 5B)

doi: 10.1016/j.jep.2023.116257 209

Consequently, much higher concentrations of pegvisomant are necessary to reduce serum IGF1 in mice