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They are prescribed off-label by clinicians based on clinical judgment, existing research, and patient-specific factors
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"This is exactly why we have to do double-blind placebo-controlled studies, to look not only at the efficacy, as we hope, but also safety, in particular, because people with alcohol use disorder and addiction in general often have a comorbidity with other mental health problems, including depression," Leggio said, stressing the importance of monitoring closely for depressive symptoms
Review article: the physiological effects and safety of peppermint oil and its efficacy in irritable bowel syndrome and other functional disorders
