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Peptides occupy a central position in AD pathobiology: pathogenic species such as A oligomers and tau-derived fragments drive synaptic failure, mitochondrial dysfunction, and neuroinflammation, whereas several endogenous neuropeptides exert compensatory neuroprotective, trophic, or homeostatic effects
Furthermore, ongoing developments on the use of GLP-1 receptor agonists beyond diabetes in neurodegenerative diseases, cardiovascular conditions, and even obstructive sleep apnea, are propelling the global GLP-1 receptor agonist market growth
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JAMA, 327 (2), 138-150
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