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doi:10.1177/0194599818797598

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Medical Evaluation : Your healthcare provider will evaluate your overall health, any pre-existing conditions, and current medications to ensure that transitioning to Tirzepatide is safe

Similarly, increased ubiquitylation of proteasome-associated subunits like PSMA1 and PSMB4, and autophagy-related proteins such as sequestosome-1 (SQSTM1) was detected across multiple sites (Fig