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While the first GLP-1 drug was FDA-approved in 2004, this class of drugs has a long, little-known history dating back to the 1980s

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This multi-receptor activation differentiates retatrutide from monotherapy and dual-agonist compounds, positioning it as a significant research tool for investigating metabolic disorders

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The direct-start group experienced nearly double the rate of GI adverse events

With obesity affecting about 40% of U.S