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Murray, S

Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG)

Activating upstream targets of the GSH system The key upstream target for GSH system modulation is generally considered to be Nrf2, a redox-sensitive regulator

Inzucchi 2012a)

It was only recognized in the late 1980s that desensitization of insulin secretion, which describes a state of decreased secretory responsiveness of -cell to the glucose stimuli, is a pathophysiological phenomenon of -cell function and not just an in vitro artifact 30

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