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Liver Benefits Non-alcoholic fatty liver disease (NAFLD) and its more severe form, non-alcoholic steatohepatitis (NASH), affect a large proportion of patients with Type 2 diabetes

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Fernandes Gomes B, Kumar A, Ashton NJ et al (2024) Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders

Tirzepatide, in particular, has shown dramatic reductions in hepatic fat fraction in clinical trials

The resulting catastrophic energy deficit is a primary physiological driver of post-exertional malaise (PEM) or 'crashes,' where even minor, everyday activities trigger a disproportionate and prolonged exacerbation of profound fatigue, muscle weakness, and cognitive impairment