Even as the preferred GLP-1, Wegovy typically requires prior authorization (pre-approval from your insurer)
This product is supplied as a co-lyophilized powder containing 5mg of CJC-1295 and 5mg of Ipamorelin in a single vial
In human gut microbiota analyses, one study reported increases in Faecalibacterium prausnitzii and Peptostreptococcus anaerobius (Bacillota) , as well as Bacteroides vulgatus (Bacteroidota) and Akkermansia muciniphila (Verrucomicrobiota ) ( 45)
Furthermore, decreased NAD+ levels, potentially a consequence of reduced kynurenine, may contribute to fatigue by impairing energy production, and disrupting the coordination of circadian rhythms necessary for effective sleep (reviewed in Dehhaghi et al., 2022)
Patients with higher levels of fibrotic markers like S100A4 in blood or peritoneal fluid may be put on an anti-fibrotic regimen on priority
Methylcobalamin is our recommendation for adults 60+