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Start with once-daily application and observe for any reaction before increasing to twice daily
Mol Pharmacol 55:263268 [DOI] [PubMed] [Google Scholar] Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, et al
9:e92900
Who Should Approach GHK-Cu with Caution Individuals with known copper sensitivity, Wilson's disease, or active systemic inflammation should discuss GHK-Cu with a qualified healthcare provider before use
(10) Shuzhen Mao, Jiahui Huang, Junyan Li, Fang Sun, et al (2025) Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms Frontiers in Pharmacology, 2025 Jul 2, Volume 16, Page 1551843