There was also a significant increase in the insulinogenic index in the high GLP-1 compared to the low GLP-1 group at 12 weeks [between group difference 17.9 (95% CI 1.76, 34.04)] ( Table 4 )
For someone with previous diverticulitis, these shifts in bowel function need careful monitoring
Individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia type 2 (MEN2) should discuss this with their clinician before considering any GLP-1based therapy, and should be alert to symptoms such as a neck lump, hoarseness, or difficulty swallowing
Scientific Reports, 10 , 12235
10.1038/288675a0 10 AmiriM.MasroorM
Factors such as skin type, melanin production, lifestyle, dosage, and overall health play a role in the speed of skin whitening