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All authors made substantial, direct and intellectual contribution to the work, and revised the manuscript

It exhibits an IC 50 of approximately 1 M for NNMT inhibition 4 , with favorable pharmacokinetic properties

Additionally, the ELISA results demonstrated that both Fer-1 and QCT significantly alleviated the inflammatory and angiogenic imbalance

It is known that acetyl groups possess membrane penetration ability, which can enhance the passive cellular transport of hydrophilic small molecules and a higher content of acetyl groups was appeared in AA-CDs

These variables contribute to the model's explanatory power, as reflected in their relatively large mean squares and F-values

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