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Importantly, along with an induction of HIF1, in SCD erythroblasts cultured in the absence of hemin, we detected a significantly decreased CBS expression under hypoxia compared to normoxia (Supplementary Fig

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Notably, immunoblot analysis revealed that TNF induced EAAT3 expression in MTEC-WT cells, while the NF-B inhibitor BMS 345541 suppressed EAAT3 expression in MTEC-KO cells (Fig

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