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CSF fraction within the voxel ranged from 7 to 25% (mean 17%, 4.9% s.d.)

Licofelone, as an mPGES-1 inhibitor, has succeeded in reaching the required criteria in phase III clinical trials for treating osteoarthritis

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In FoxO1/3/4 knockout mice, ubiquitination and autophagy flux are nearly abolished, confirming the pivotal role of ROS-FoxO signaling in muscle wasting (Figure 8 shows the ROS-mediated activation of FoxO signaling in muscle protein degradation