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Dixon D, Edmonds M

Piochon, C

What is fascinating is that their effects are not limited to alcohol: preclinical and correlational data indicate possible benefits in decreasing use of nicotine and opioids, which makes sense as alcohol, cannabis, opioid, and nicotine use disorders cluster together genetically into one brain disorder

Proteostatic pathways are deregulated in middle-aged and aged Mda5 -/- HSCs To investigate the molecular mechanism underlying the youthful phenotype of Mda5 -/- HSCs, we performed bulk RNA-sequencing (RNA-seq) to compare young, middle-aged, and aged WT and Mda5 -/- HSC transcriptomes

Mol Psychiatry 18:595606