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The extreme fluctuations between hyperglycemia and relative hypoglycemia can cause significant tiredness, brain fog, and lethargy

GLP-1 and GIP are intestinal hormones that are normally secreted when food is consumed, and they act on the pancreas to promote insulin secretion and lower blood sugar levels

(PubMed) Guilarte TR, Wagner HN, Jr., Frost JJ

The Acute Neurology Survival Guide: A Practical Resource for Inpatient and ICU Neurology (1st ed

That means that they stimulate the body to produce and secrete its own growth hormone

Physiological Basis The delay in gastric emptying induced by GLP-1 receptor agonists (GLP-1 RAs) arises from a coordinated modulation of gastrointestinal motility under central vagal control