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Department of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland Abstract Reactive oxygen and nitrogen species can be generated endogenously (by mitochondria, peroxisomes, and phagocytic cells) and exogenously (by pollutions, UV exposure, xenobiotic compounds, and cigarette smoke)

One of the key contributors to the aging phenotype is the generation of reactive oxygen species (ROS)

This committee planned the questions on the basis of the findings from the scoping review and identified seven experts [10]three endocrinologists, two cardiologists, and two nephrologistschosen according to their expertise in treating people with diabetes and their experience in formulating local guidelines or leading the implementation of policies within the healthcare system

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