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Nevertheless, women should not assume that everything remains unchanged during therapy

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Such a trial would likely take several years and cost tens of millions of dollars, but the potential payoff, a new treatment option for a condition that affects over a billion people worldwide, justifies the investment

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However, under zinc excess, lysosomal destabilization and leakage of cathepsin D into the cytosol can trigger mitochondrial damage and apoptosis via the lysosomemitochondria axis 168