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PMID: 18315507

* Correspondence: Jiangjiang Pu, [email protected]

For GHK-Cu, the best-supported claims come from topical and wound-related evidence, while injectable and systemic claims need more rigorous human data [2], [3], [8]

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Considering the many limitations of intravenous glutathione, it is prudent that dermatologists refrain from administering such injections for skin lightening until further trials and high quality studies establish a favourable benefit versus risk ratio that justify its use [Box 7]