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Low levels might indicate certain health conditions, but it's often used alongside other tests for a complete picture.

Diabetes Care 42 , S46S60 (2019)

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There are a few common, mild side effects associated with B12 shots, including: Mild diarrhea, itching, nausea and vomiting, dizziness, headaches, and hot flashes Redness or swelling at the injection site Temporary soreness at injection site Serious side effects are rare but require immediate medical attention

If stores of b12 had been available to me surely that would not have been the case

The two major degradation pathways that generate HVA begin with oxidative deamination by monoamine oxidases (MAOs), or O-methylation by catechol-O-methyltransferase (COMT)