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The use of catalytic anticancer agents could reduce the therapeutic doses needed to achieve the desired therapeutic effect

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Mechanistically, metformin may activate Nrf2 through multiple pathways, including AMPK activation, inhibition of GSK-3mediated Nrf2 degradation, and modulation of intracellular redox homeostasis, all of which facilitate Nrf2 nuclear translocation and subsequent induction of downstream antioxidant genes 48,49

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From the best foods and nutrients to seek out, to balancing your mind, body and spirit with self-care, to the health screenings that are most essential the doctors share what you need to know