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TXNRD plays an important role in maintaining the redox balance and has protective role inside dopaminergic cells, which are prone to oxidative stress, e.g., under parkinsonian degeneration (Lopert et al., 2012)

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[DOI] [PubMed] [Google Scholar] 5.Geer E.B., Islam J., Buettner C

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, the covalent binding of NAPQI to the thiol groups of critical cellular proteins (following glutathione depletion), oxidative stress induced directly by NAPQI or via coproduction of reactive oxygen species (superoxide radical and hydrogen peroxide) through redox cycling between the paracetamol semiiminoquinone radical and NAPQI) (1, 2), and vice versa, these processes counteraction may be involved in BPC 157 beneficial effects

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