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Diabetes care 40 , S75S87 (2017)

Moreover, a minor proportion of this agent can be metabolized within the liver by the cytochrome P450 enzymes (primarily by CYP2E1) to NAPQI, which is detoxified by conjugation and excreted in the glutathione or NAC forms ( Figure 2 )

Oxidative Stress: High-sugar diets can increase the production of reactive oxygen species (ROS), overwhelming the brains antioxidant defences and damaging neurons through oxidative stress

The friction of arranging, paying for, and waiting on labs is not trivial

Similarly, an antibiotic trial in AD aimed at altering the microbiome did not yield cognitive improvement over placebo [284, 285]

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