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The sex determination pathway helps to regulate differentiation of the meiotic germ cells first into sperm during L4 stage, which then switch to differentiation into oocytes 18

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Discussion The present study reported that the use of a combination of nutraceutical compounds, specifically acetyl-L-carnitine, L-carnitine, L-ARG and NAC, was effective in reducing IR and in improving insulin sensitivity and HIE in obese PCOS patients