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A typical protocol involves injections weekly for several weeks, then gradually reducing in frequency as levels stabilise

doi: 10.1038/s41419-024-06939-5

Human studies conducted to date generally involve small sample sizes, heterogeneous dosing regimens, and relatively short intervention periods, restricting the ability to draw robust conclusions regarding efficacy, optimal dosage, and treatment duration

Laboratory studies in renal function demonstrate that FOXO4-DRI administration restores kidney function in both accelerated aging models and naturally aged mice, indicating that senescent cell elimination can reverse organ-specific age-related deterioration

Packaging, vial appearance, powder quantity, and batch presentation may vary between production batches

Hermann A, Varga V, Oja SS, Saransaari P, Janky R