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IGF-I binds to three receptors, and the binding to IGFIR promotes cell proliferation, survival, differentiation, and migration
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However, major caveats include dramatic differences in the gene expression profile compared to primary hepatocytes [138]
Differences between long COVID and ME/CFS cohorts While both groups shared oxidative stress signatures, long COVID participants showed lower levels of ATP (energy currency of cells) and the protective enzyme mitochondrial superoxide dismutase
