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The authors also comment that there is common agreement that ME/CFS is associated with changes in acylcarnitine and l-carnitine homeostasis, which is confirmed in the one patient which was tested in this study

However, this is rare and usually occurs in individuals with pre-existing conditions such as epilepsy

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To assess the DHT adoption rate in rare disease clinical trials, we conducted a targeted search on ClinicalTrials.gov for all interventional trials related to the ten selected rare diseases, starting from 2017the first year in which more than ten DHT-enabled trials appeared in our dataset