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For example, HCC-derived -fetoprotein (AFP) skews DCs toward glycolysis dependency while suppressing fatty acid metabolism and impairing functional maturation and the expression of costimulatory ligands [118]

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Clinical recommendations based upon the patients renal function include [see DOSAGE AND ADMINISTRATION and CLINICAL PHARMACOLOGY ]: Before initiating SYNJARDY or SYNJARDY XR, obtain an estimated glomerular filtration rate (eGFR)