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Since 2016, large cardiovascular outcome trials (CVOTs) have demonstrated that several GLP-1RA not only improve glycemic control and body weight but also reduce major adverse cardiovascular events (MACE) and slow CKD progression

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Use with caution in cats with a history of neurologic disorders

The Phase II detoxification pathway, in which glutathione plays the central role, represents the critical step that converts potentially harmful substances into water-soluble compounds suitable for elimination

IGF1R activation via DES(1-3) IGF-1 induced a 2.8-fold increase in S-phase cell population, reversing the 50% S-phase reduction produced by gefitinib monotherapy