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Data availability The Raw shotgun sequencing data that support the findings of this study have been deposited in the European Nucleotide Archive under accession codes PRJEB37249, PRJEB38742, PRJEB41311, and PRJEB46098

The trial, conducted across multiple international sites and involving 725 adults living with obesity or overweight but without type 2 diabetes, concluded in April 2026 after 76 weeks of treatment

Most people begin developing gray or silver hair before the Eating the right nutrients and taking other proactive measures may help preserve existing pigmentation, delaying overall graying

Refer patients who dont respond to lifestyle or pharmacological therapies

It does not cause dependence, does not interact with GLP-1 receptor agonists, and works through an osmotic mechanism rather than stimulating the colon directly

Frequently asked questions No