Semaglutide and Tirzepatide are originally developed to manage type 2 diabetes
Compounded versions permit intermediate doses that branded pens dont, which is where 503A prescriptions earn their flexibility in the tirzepatide vs semaglutide conversation
Accessed October 15, 2025
The agency will continue to work with manufacturers to help resolve the current shortages, and, as shortages resolve, will closely monitor the situation and provide any assistance we can to help manufacturers ensure an adequate supply
Semaglutide mimics GLP-1, promoting fullness and regulating blood sugar, while Tirzepatide targets both GLP-1 and GIP receptors for enhanced effectiveness
If you are using an Ozempic pen that is already in use (meaning you have already taken at least one dose from it), the manufacturer allows storage at room temperature between 59 and 86 degrees Fahrenheit for up to 56 days