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NAD+ is also a signaling molecule that tells DNA to increase transcription and translation to produce more proteins than the cells need to produce energy

The priming signal involves the upregulation of NLRP3 expression and the synthesis of proinflammatory cytokines such as TNF- and IL-1, typically mediated by nuclear factor kappa B activation in response to inflammatory stimuli

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European Journal of Pharmaceutical Sciences

GPX4 is lowly expressed in gastric cancer (GC) cells, making them more susceptible to ferroptosis than normal intestinal cells

doi: 10.3389/fimmu.2023.1225948 44 FanJToKKWChenZSFuL