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Under physiological conditions, the cyclic recruitment of primordial follicles and the gradual reduction in oocyte quality result in a year-by-year decrease in ovarian reserve, ultimately leading to its exhaustion after menopause

15 found that fentanyl-induced analgesia, decreased tidal volume (Vt) and increased Alveolar-arterial (A-a) gradient (ventilation-perfusion mismatch) 16 , was reduced by a peripherally-restricted -OR antagonist, naloxone methiodide

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Why Mechanism Does Not Guarantee Clinical Results Mechanistic findings are useful for hypothesis-building, but clinical outcomes require human studies with defined populations, formulations, controls, durations, and endpoints

Testosterone attenuates sevoflurane-induced tau phosphorylation and cognitive impairment in neonatal male mice

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