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Long-term continuous use lacks safety data, so periodic breaks are generally recommended

He has also received grants from Medical Research Council, European Union, JPND, Alzheimers Research, UK, Alzheimers Drug Discovery Foundation, Alzheimers Society, UK, Alzheimers Association, US, Medical P.E

Moreover, PD-1 inhibitors, in particular, were associated with hypothyroidism as compared to CTLA-4 inhibitors (odds ratio (OR): 1.89