If severe reflux symptoms develop, the dose may be adjusted, or additional medications may be prescribed to manage the reflux
Semaglutide 2 4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
(2023) Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action Muller, Neerav et al
The most common side effect of the GLP-1RA class is GI-related adverse events (AE) including nausea, diarrhea, and vomiting (129) which are dose-dependent and typically present in the up-titration phase
Biochemistry and hematology tests are conducted at screening, and at weeks 13, 26, 52, 78, 104, and 156
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