In cases, the drugs may cause ileus, a digestive problem leading to bowel movement difficulties
The mechanism of action was later discovered to be chemically-mediated mitochondrial uncoupling put very simply, chemicals knock holes in the mitochondrial membrane and force the mitochondria to work really hard to reverse the dissipation of membrane potential, which generates heat and reduces weight
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Its genetic simplicity, short life cycle, ease of genetic manipulation, and high reproductive capacity provide researchers with a cost-effective platform for investigating complex neurodegenerative mechanisms