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the first factor was considered a validated latent construct underlying the variables

[DOI] [PubMed] [Google Scholar] 42.Galinari ., Sabry D.A., Sassaki G.L., Macedo G.R., Passos F.M.L., Mantovani H.C., Rocha H.A.O

Per ADA 2026 Standards of Care, patients with presymptomatic Type 1 DM (stage 12) may be identified by autoantibody screening before frank hyperglycemia occurs

This hypothesized VEGF/VEGFR interaction may activate a complex intracellular signaling cascade, which may involve multiple proteins such as phospholipase C, protein kinase C, and the mitogen-activated protein kinases

Statistical analysis Measures of central tendency and dispersion were calculated, including geometric means, medians, 25th and 75th percentiles, minimum and maximum for total, pro- and mature BDNF levels

Figure 4 illustrates the key mitochondrial antioxidant defense systems against ROS