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The presence of adequate circulating T 4 and T 3 feeds back at the level of both the hypothalamus and pituitary, decreasing TRH and TSH production ( Figure 2 )
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Easier said than done, I know really having a hard look in middle age, is your career path serving you or killing you, is the job that you're working, really doing bad things to your stress levels, and if so, do you have the courage and the wherewithal to shift that so that it doesn't take you to an early grave