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The project, which is comprised of 43 injection wells to provide a freshwater pressure ridge and 4 extraction wells to form a trough which breaks the landward gradient of intruding seawater, is located near the Los Angeles-Orange County line about two miles inland from the mouth of the San Gabriel River

These effects include altered substrate utilization, OXPHOS dysfunction, impaired ATP synthesis, and mitochondrial dysfunction

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SPX causes an excessive generation of ROS, which leads to malfunction of the mitochondria and thus inhibits FLS under ultrasonic circumstances

In that sense, estrogen treatments appear to promote the number of proliferating cells and synaptic biomarkers in the hippocampus (Sopova et al., 2014)

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