No published human pharmacokinetic programme was identified
For severe cases, the first dose is usually 1,000 mcg given intramuscularly every day or every other day for a week or two
[7] Clinicians should exercise extreme caution in advanced chronic kidney disease or sarcoidosis, tuberculosis, and other granulomatous disorders where extrarenal 1-hydroxylase activity can generate excess calcitriol and precipitate hypercalcaemia even at modest serum 25-hydroxyvitamin D concentrations
Int J Hematol
Sterile Water for Injection, USP is specified as containing no bacteriostat, antimicrobial agent or added buffer, so nothing suppresses microbial growth once the seal is broken, and it is treated as a single-use article
It is not approved by the FDA or any other regulatory body for human or veterinary use, and nothing in this guide constitutes guidance for human administration