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Non-adherent cells were transferred to fresh medium every 23 days for a total of at least 23 days to remove adherent macrophages and fibroblasts

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The sNDA was based on results from the Phase 3, double-blind, parallel-group, placebo-controlled cardiovascular outcomes trial, SOUL. The trial reported a 14% reduction in the risk of MACE compared to placebo when added to standard of care in patients with T2DM and established CVD and/or CKD

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These variants influence appetite regulation, glucose metabolism, and how strongly your body's natural GLP-1 and GIP systems respond to receptor activation

This ensures that the donor has a sufficient blood volume to safely undergo the plasmapheresis process without adverse effects