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However, rare but severe side effects, such as pancreatitis or gallbladder issues, require immediate medical attention

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J Biol Chem 1993;268:196505.ArticlePubMed 36

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Irrespective of TMAO associations with individual species, similarly to BMIS multivariate PERMANOVA analysis uncovered a significant, albeit weak, association between circulating TMAO and microbiota composition ( P = 0.001