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Treatment of hypertension during pregnancy as a replacement for ACE inhibitors & ARBs The patient can be switched back to an ACE inhibitor or ARB once pregnancy is over Notes: Methyldopa is the L-isomer of alpha-methyldopa References: Benowitz NL (2024): Antihypertensive Agents (Chapter 11)

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Front Pharmacol 2017

Magnesium ions act to shut the NMDA receptors cationic channel and block the entry of ions into neurons under physiological conditions

Depositions of extracellular amyloid plaques and intracellular neurofibrillary tangles in the hippocampus and cortex are striking features of Alzheimers disease

doi: 10.1111/ijcp.13576 39 MastC.DardevetD.PapetI