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37% GLP-1 users saw a 37% reduction in hospitalizations caused by MACE over the 24 months following therapy initiation

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Interestingly, -cell specific deletion of Foxa2 also results in postnatal death due to severe hypoglycemia, but the low glucose level in Foxa2-negative mice seems to be caused by hyperinsulinemia rather than by changes in Gcg expression [121]